Emphasis On Coating
A World Apart
In a World of Parts!
Precision Chemical Etching
Our process of photochemical etching
offers the speed, flexibility and
precision demanded by
• Part to print in 1 day... yes, we’re that fast!
• Our technical staff will drive
your project, even without a print.
• Unlimited flexibility and complexity!
• We can form, plate, assemble and
package your parts...
Just tell us what you need!
You’ll see the difference as soon as you
talk to us. Contact our sales staff or request
your free sample kit and design guide at
773.463.6211 3758 W. Belmont Avenue
FAX.463.3387 Chicago, IL 60618
The means by which a therapeutic coating is
applied to an implant can significantly impact
the performance of the coating. A variety of
coating techniques enable conformal coatings
as well as coatings that cover only a portion
of the device, such as a luminal or abluminal
coating, which enables targeted delivery to spe-
cific tissues in contact with the device. Coating
techniques offer control over the thickness of
the coating, which can be adjusted to provide
a sufficient reservoir for the therapeutic agent
while not causing a large dimensional change
to the device that may hinder delivery, place-
ment, or other attributes. For solvent-based
coating processes, the rate at which the solvent
is dried from the coating can affect the struc-
ture of the coating and the drug release rate.
Slower dry times, for example, can allow for
greater segregation of the drug from the poly-
mer, resulting in an enrichment at the surface
of either the drug or polymer compared to the
bulk coating composition. Solvent evaporation
and other aspects of the coating process can
also impact the form of the drug (crystalline,
amorphous, etc.), which can, in turn, influence
how quickly the drug elutes from the coating
and how rapidly the drug is absorbed into the
The use of therapeutic coatings on medical devices has led to enhanced device performance
and improved patient outcomes. The selection
of coating materials, therapeutic agent, and
processing methods all play a critical role
in the deliverability, therapeutic effect, and
duration of therapy. A skilled development
team can help navigate the interconnectedness
of the coating choices to ensure the desired
therapeutic properties are achieved.
For more information, visit www.surmodics.com.
Figure 4: Durable coating on a stent
Figure 5: Degradable coating on the abluminal
side of a stent