With HiQ DIALOG.
17 more output.
tools and enjoy a heightened degree of control, predicting, and planning
appropriately for all circumstances. A well-designed system can become a
platform to help monitor disease state progression, so devices designed with
enabling technologies can help support the collection of information regarding physiologic measure, use patterns, adherence, and other relevant aspects
of disease management.
The Device Landscape
A breadth of options exist for insulin delivery devices. Delivery and administration of insulin consists of three options: syringe, pen, and pump, with
pens holding the largest segment in the insulin delivery device market with
over 50 percent of the share. 4 Patients rely heavily on the advice of their
physician regarding recommendations for devices, but many are unaware of
alternative devices or may lack device-specific training. Challenges for each
segment are varied.
While syringe systems are the most affordable method for insulin delivery
and offer a straight-forward approach to care, challenges include portability,
increased pain from larger needles, and accidental needle sticks. Patients may
also be embarrassed using a syringe because of its association with drug addicts.
Pen devices offer enhanced portability and convenience. Because the
device is prefilled and easily assembled, it does not carry the same stigma as a
syringe. However, many users may find the size of the injector inconvenient
for multiple daily injections. In addition, since the cartridge is hidden, insulin
visibility may be obstructed, and the pen cartridges carry less insulin than
vials, causing supplies to be used more quickly.
Wearable pumps offer freedom, flexibility, and control through fewer injections and continuous insulin release. Pumps may reduce the steps involved in
administering an insulin dose, thus mitigating the need to carry supplies. The
device is also discrete because it is worn on the body under clothing. There
are, however, misconceptions around pump use with patients often seeing
the pump as a sign that the disease has progressed. Device malfunction and
failure is also a concern, while others may not like the feel of being “attached”
to the device.
Until a cure is available, trends in insulin delivery are streaming toward
seamless integration into the patient’s life, simplicity, and convenience, as
well as fewer painful injections. Newer options include closed-loop systems
that combine blood glucose measurement with automatic dose adjustment;
patch pumps with an integrated needle that eliminates a separate tubing and
catheter set; programmable integration with existing lifestyle technology; and
potential changes to administration, including possible oral medications. Such
changes to delivery systems may improve adherence and allow patients to
manage their condition better. While some therapies, such as GLP-1 drugs
used as an adjunct to insulin therapy, can reduce the number of injections
needed while improving control of the condition, designing devices that are
automated, accommodating, affliction-free, and affordable will help to provide
flexibility, reduce pain, and foster adherence until a cure is developed. MDT
For more information, visit www.westpharma.com.
1 World Health Organization, Diabetes Fact Sheet
2 IDF Diabetes Atlas 2012, 5th ed.
3 CDC 2011 National Diabetes Fact Sheet, UnitedHealth Group (UHG), GBI
4 GBI Report, Diabetes Care Devices Market to 2018
A variety of options exist for diabetes management and
insulin delivery, including syringe systems, pen injectors,
and wearable insulin pumps.